Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Sodium Valproate requires a valid prescription.
Sodium Valproate
Generic Name: VALPROATE SODIUM
11 DESCRIPTION Valproate sodium is the sodium salt of valproic acid designated as sodium 2-propylpentanoate.
Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)
Common Brand Names in India:
What is Sodium Valproate Used For?
- Women with epilepsy or bipolar disorder who are pregnant or
- Valproate sodium injection is also indicated for use as sole and adjunctive therapy in the treatment...
- Simple absence is defined as very brief clouding of the sensorium or loss of consciousness accompani...
- Complex absence is the term used when other signs are also present.
How Does It Work?
The mechanisms by which valproate exerts its therapeutic effects have not been established.
Dosage & Administration
- 2 DOSAGE AND ADMINISTRATION Valproate sodium injection is intended for intravenous use only. • Epilepsy o Complex Partial Seizures in Adults and Children 10 years of age or older: Initial dose is 10 to 15 mg/kg/day, increasing at 1 week intervals by 5 to 10 mg/kg/day to achieve optimal clinical response.
- Maximum recommended dose is 60 mg/kg/day ( 2.1 ). o Simple and Complex Absence Seizures: Initial dose is 10 to 15 mg/kg/day, increasing at 1 week intervals by 5 to 10 mg/kg/day to achieve optimal clinical response.
- Maximum recommended dose is 60 mg/kg/day ( 2.1 ). 2.1 Epilepsy Valproate sodium injection is for intravenous use only.
Side Effects
Common Side Effects
Serious Side Effects (seek immediate medical attention)
Warnings & Precautions
- However, healthcare providers should not rely totally on serum biochemistry since these tests may not be abnormal in all instances, but should also consider the results of careful interim medical history and physical examination.
- Caution should be observed when administering valproate products to patients with a prior history of hepatic disease.
- Patients on multiple anticonvulsants, children, those with congenital metabolic disorders, those with severe seizure disorders accompanied by mental retardation, and those with organic brain disease may be at particular risk.
Drug Interactions
Sodium Valproate may interact with the following medicines. Always inform your doctor about all medications you are taking.
Storage Instructions
Store at room temperature, away from moisture and heat.
Need a Prescription or Medical Advice?
Consult a qualified doctor before taking Sodium Valproate. Our verified doctors are available for in-clinic and online consultations.
Other Neurological Medicines
Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.
FAQS
Sodium Valproate – Frequently Asked Questions
Common questions about Sodium Valproate, its uses, dosage and safety.
Sodium Valproate is used for: Women with epilepsy or bipolar disorder who are pregnant or, Valproate sodium injection is also indicated for use as sole and adjunctive therapy in the treatment..., Simple absence is defined as very brief clouding of the sensorium or loss of consciousness accompani..., Complex absence is the term used when other signs are also present..
Sodium Valproate is available in India under the brand names: Valproate Sodium.
Sodium Valproate is a prescription-only medicine. You need a valid prescription from a registered doctor to purchase it.
Common side effects of Sodium Valproate include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Dry mouth, Insomnia. Serious but less common side effects include: Serious, Anaphylaxis, Agranulocytosis, Aplastic, Seizure. Consult your doctor if you experience any severe symptoms.
The mechanisms by which valproate exerts its therapeutic effects have not been established.
Sodium Valproate may interact with: Aspirin, Topiramate, Valproate, Caution, Estrogen, Hormonal, Felbamate, Rifampin. Always inform your doctor about all medicines, supplements, and herbal products you are taking.
Elderly patients may be more sensitive to Sodium Valproate. Dose adjustments are often needed due to reduced kidney and liver function. Always consult a doctor before use in patients over 65 years of age.
The safety of Sodium Valproate during pregnancy has not been fully established. Consult your obstetrician or gynaecologist before taking Sodium Valproate if you are pregnant or planning to become pregnant.
The price of Sodium Valproate varies by brand and formulation. Common brands include Valproate Sodium. Check with your local pharmacy or an online pharmacy for current pricing. Generic versions are generally more affordable than branded ones.
If you miss a dose of Sodium Valproate, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. Consult your doctor if you frequently forget doses.
Medical Disclaimer
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