Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Pramipexole requires a valid prescription.

NeurologicalPrescription RequiredORAL

Pramipexole

Generic Name: PRAMIPEXOLE DIHYDROCHLORIDE

Pramipexole dihydrochloride extended-release tablets contain pramipexole dihydrochloride (as a monohydrate).

Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)

Common Brand Names in India:

Mirapex

What is Pramipexole Used For?

  • Parkinson's disease
  • Parkinson’s disease (PD) (1)

How Does It Work?

The precise mechanism of action of pramipexole as a treatment for Parkinson's disease is unknown, although it is believed to be related to its ability to stimulate dopamine receptors in the striatum.

Dosage & Administration

  • Assess therapeutic response and tolerability at a minimal interval of 5 days or longer after each dose increment. Patients may be switched overnight from immediate-release pramipexole tablets to extended-release pramipexole tablets at the same daily dose.
  • Dose adjustment may be needed in some patients Pramipexole dihydrochloride extended-release tablets should be discontinued gradually. 2.1 General Dosing Considerations Pramipexole dihydrochloride extended-release tablets are taken orally once daily, with or without food.
Always follow your doctor's prescription. Do not self-medicate or change doses without medical advice.

Side Effects

Common Side Effects

NauseaVomitingDiarrheaConstipationHeadacheDizzinessFatigueDry mouth

Serious Side Effects (seek immediate medical attention)

SeriousRhabdomyolysis

Warnings & Precautions

  • If a decision is made to continue pramipexole dihydrochloride extended-release tablets, advise patients not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolent.

Who Should NOT Take This?

  • None.

Drug Interactions

Pramipexole may interact with the following medicines. Always inform your doctor about all medications you are taking.

Dopamine

Storage Instructions

Store at room temperature, away from moisture and heat.

Speak to a neurologist on Zospital

Consult a neurologist on Zospital before starting Pramipexole. Verified Indian specialists available for in-clinic and online consultations.

Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.

FAQS

Pramipexole – Frequently Asked Questions

Common questions about Pramipexole, its uses, dosage and safety.

Pramipexole is commonly prescribed in India for: Parkinson's disease, Parkinson’s disease (PD) (1). Always confirm the indication with a registered medical practitioner before starting any course.

Pramipexole is sold in India under brand names such as Mirapex. You can also find it on online pharmacies like 1mg, Pharmeasy and Apollo Pharmacy.

Pramipexole is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.

Common side effects of Pramipexole can include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Fatigue, Dry mouth. Less common but serious side effects can include: Serious, Rhabdomyolysis. Stop the medicine and contact your doctor immediately if any of these appear.

The precise mechanism of action of pramipexole as a treatment for Parkinson's disease is unknown, although it is believed to be related to its ability to stimulate dopamine receptors in the striatum.

Pramipexole can interact with: Dopamine. Tell your doctor about every medicine, supplement and herbal product you take — including ayurvedic and homeopathy preparations — before starting Pramipexole.

Indian guidelines often recommend lower starting doses of Pramipexole for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.

Pregnancy safety of Pramipexole depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Pramipexole during pregnancy or while planning conception.

Prices in India typically range from ₹30 – ₹500 per strip / vial depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.

If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Pramipexole's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.

You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.

Medical Disclaimer

The content provided on Zospital is for general informational and educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call your doctor or emergency services immediately.

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