Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Lamotrigine requires a valid prescription.
Lamotrigine
Generic Name: LAMOTRIGINE
Lamotrigine, USP an AED of the phenyltriazine class, is chemically unrelated to existing AEDs.
Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)
Common Brand Names in India:
How Does It Work?
Lamotrigine also displayed inhibitory properties in the kindling model in rats both during kindling development and in the fully kindled state.
Dosage & Administration
- Dosing is based on concomitant medications, indication, and patient age. ( 2.1 , 2.2 , 2.3 , 2.4 ) To avoid an increased risk of rash, the recommended initial dose and subsequent dose escalations should not be exceeded.
- The risk of nonserious rash may be increased when the recommended initial dose and/or the rate of dose escalation for lamotrigine orally disintegrating tablets are exceeded and in patients with a history of allergy or rash to other AEDs.
Side Effects
Common Side Effects
Serious Side Effects (seek immediate medical attention)
Warnings & Precautions
- Life-threatening serious rash and/or rash-related death: Discontinue at the first sign of rash, unless the rash is clearly not drug related. ( Boxed Warning , 5.1 ) Hemophagocytic lymphohistiocytosis: Consider this diagnosis and evaluate patients immediately if they develop signs or symptoms of systemic inflammation.
- Any expected or observed benefit of lamotrigine in an individual patient with clinically important structural or functional heart disease must be carefully weighed against the risk for serious arrythmias and/or death for that patient. Blood dyscrasias (e.g., neutropenia, thrombocytopenia, pancytopenia): May occur, either with or without an associated hypersensitivity syndrome.
- There is evidence that the inclusion of valproate in a multidrug regimen increases the risk of serious, potentially life-threatening rash in pediatric patients.
Who Should NOT Take This?
- Lamotrigine is contraindicated in patients who have demonstrated hypersensitivity (e.g., rash, angioedema, acute urticaria, extensive pruritus, mucosal ulceration) to the drug or its ingredients [see Boxed Warning , Warnings and Precautions ( 5.1 , 5.3 )].
- Hypersensitivity to the drug or its ingredients. ( Boxed Warning , 4 )
Drug Interactions
Lamotrigine may interact with the following medicines. Always inform your doctor about all medications you are taking.
Storage Instructions
Store at room temperature, away from moisture and heat.
Speak to a neurologist on Zospital
Consult a neurologist on Zospital before starting Lamotrigine. Verified Indian specialists available for in-clinic and online consultations.
Other Neurological Medicines
Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.
FAQS
Lamotrigine – Frequently Asked Questions
Common questions about Lamotrigine, its uses, dosage and safety.
Lamotrigine is sold in India under brand names such as Lamictal, Lametec, Lamitor, Subvenite, Lamotrigine. You can also find it on online pharmacies like 1mg, Pharmeasy and Apollo Pharmacy.
Lamotrigine is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.
Common side effects of Lamotrigine can include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Fatigue, Dry mouth. Less common but serious side effects can include: Serious, Death, Agranulocytosis, Suicidal, Seizure. Stop the medicine and contact your doctor immediately if any of these appear.
Lamotrigine also displayed inhibitory properties in the kindling model in rats both during kindling development and in the fully kindled state.
Lamotrigine can interact with: Uridine, Administration, Additional, Clinical, Concentration, Lamotrigine. Tell your doctor about every medicine, supplement and herbal product you take — including ayurvedic and homeopathy preparations — before starting Lamotrigine.
Indian guidelines often recommend lower starting doses of Lamotrigine for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.
Pregnancy safety of Lamotrigine depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Lamotrigine during pregnancy or while planning conception.
Prices in India typically range from ₹30 – ₹500 per strip / vial depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.
If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Lamotrigine's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.
You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.
Medical Disclaimer
The content provided on Zospital is for general informational and educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call your doctor or emergency services immediately.