Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Pregabalin + Methylcobalamin requires a valid prescription.
Pregabalin + Methylcobalamin
Generic Name: PREGABALIN
Pregabalin is described chemically as ( S )-3-(aminomethyl)-5-methylhexanoic acid.
Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)
What is Pregabalin + Methylcobalamin Used For?
- Neurological disorders
- Seizure disorders
- Neuropathic pain
How Does It Work?
Although the mechanism of action of pregabalin has not been fully elucidated, results with genetically modified mice and with compounds structurally related to pregabalin (such as gabapentin) suggest that binding to the alpha 2 -delta subunit may be involved in pregabalin's anti-nociceptive and antiseizure effects in animals.
Dosage & Administration
- For adult indications, begin dosing at 150 mg/day.
- Maximum dose of 600 mg/day.
- Adjunctive Therapy for Partial-Onset Seizures in Pediatric and Adult Patients Weighing 30 kg or More 2 or 3 divided doses per day Maximum dose of 600 mg/day.
Side Effects
Common Side Effects
Serious Side Effects (seek immediate medical attention)
Warnings & Precautions
- Angioedema (e.g., swelling of the throat, head and neck) can occur, and may be associated with life-threatening respiratory compromise requiring emergency treatment.
- Discontinue pregabalin immediately in these patients. Antiepileptic drugs, including pregabalin, increase the risk of suicidal thoughts or behavior. Respiratory depression: May occur with pregabalin, when used with concomitant CNS depressants or in the setting of underlying respiratory impairment.
- Exercise caution when co-administering pregabalin and thiazolidinedione antidiabetic agents. 5.1 Angioedema There have been postmarketing reports of angioedema in patients during initial and chronic treatment with pregabalin.
- Exercise caution when prescribing pregabalin to patients who have had a previous episode of angioedema.
Who Should NOT Take This?
- Pregabalin capsules are contraindicated in patients with known hypersensitivity to pregabalin or any of its components.
- Known hypersensitivity to pregabalin or any of its components. ( 4 )
Drug Interactions
Pregabalin + Methylcobalamin may interact with the following medicines. Always inform your doctor about all medications you are taking.
Storage Instructions
Store at room temperature, away from moisture and heat.
Speak to a neurologist on Zospital
Consult a neurologist on Zospital before starting Pregabalin + Methylcobalamin. Verified Indian specialists available for in-clinic and online consultations.
Other Neurological Medicines
Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.
FAQS
Pregabalin + Methylcobalamin – Frequently Asked Questions
Common questions about Pregabalin + Methylcobalamin, its uses, dosage and safety.
Pregabalin + Methylcobalamin is commonly prescribed in India for: Neurological disorders, Seizure disorders, Neuropathic pain. Always confirm the indication with a registered medical practitioner before starting any course.
Pregabalin + Methylcobalamin is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.
Common side effects of Pregabalin + Methylcobalamin can include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Fatigue, Dry mouth. Less common but serious side effects can include: Severe, Serious, Life-threatening, Fatal, Suicidal. Stop the medicine and contact your doctor immediately if any of these appear.
Although the mechanism of action of pregabalin has not been fully elucidated, results with genetically modified mice and with compounds structurally related to pregabalin (such as gabapentin) suggest that binding to the alpha 2 -delta subunit may be involved in pregabalin's anti-nociceptive and antiseizure effects in animals.
Pregabalin + Methylcobalamin can interact with: Clinical. Tell your doctor about every medicine, supplement and herbal product you take — including ayurvedic and homeopathy preparations — before starting Pregabalin + Methylcobalamin.
Indian guidelines often recommend lower starting doses of Pregabalin + Methylcobalamin for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.
Pregnancy safety of Pregabalin + Methylcobalamin depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Pregabalin + Methylcobalamin during pregnancy or while planning conception.
Prices in India typically range from ₹30 – ₹500 per strip / vial depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.
If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Pregabalin + Methylcobalamin's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.
You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.
Medical Disclaimer
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