Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Tramadol requires a valid prescription.
Tramadol
Generic Name: TRAMADOL HYDROCHLORIDE
Tramadol hydrochloride is an opioid agonist in an extended-release tablet formulation for oral use.
Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)
Common Brand Names in India:
What is Tramadol Used For?
- Pain relief
- Fever reduction
- Anti-inflammatory
How Does It Work?
Although the mode of action of tramadol is not completely understood, the analgesic effect of tramadol is believed to be due to both binding to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin.
Dosage & Administration
- Do not administer tramadol hydrochloride extended-release tablets at a dose exceeding 300 mg per day.
- Because the risk of overdose increases as opioid doses increase, reserve titration to higher doses of tramadol hydrochloride extended-release tablets for patients in whom lower doses are insufficiently effective and in whom the expected benefits of using a higher dose opioid clearly outweigh the substantial risks.
Side Effects
Common Side Effects
Serious Side Effects (seek immediate medical attention)
Warnings & Precautions
- Opioid Induced Hyperalgesia (OIH) and Allodynia: Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain.
- Discontinue tramadol hydrochloride extended-release tablets if serotonin syndrome is suspected. Increased Risk of Seizures : Present within recommended dosage range.
- Avoid use of tramadol hydrochloride extended-release tablets in patients with circulatory shock. Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness : Monitor for sedation and respiratory depression.
- Avoid use of tramadol hydrochloride extended-release tablets in patients with impaired consciousness or coma. 5.1 Addiction, Abuse, and Misuse Tramadol hydrochloride extended-release tablet contains tramadol, a Schedule IV controlled substance.
- As an opioid, tramadol hydrochloride extended-release tablet exposes users to the risks of addiction, abuse, and misuse.
Drug Interactions
Tramadol may interact with the following medicines. Always inform your doctor about all medications you are taking.
Storage Instructions
Store at room temperature, away from moisture and heat.
Speak to a general physician on Zospital
Consult a general physician on Zospital before starting Tramadol. Verified Indian specialists available for in-clinic and online consultations.
Other Analgesics & Pain Relief Medicines
Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.
FAQS
Tramadol – Frequently Asked Questions
Common questions about Tramadol, its uses, dosage and safety.
Tramadol is commonly prescribed in India for: Pain relief, Fever reduction, Anti-inflammatory. Always confirm the indication with a registered medical practitioner before starting any course.
Tramadol is sold in India under brand names such as Contramal, Tramazac, Tramacip, Ultram, Dolotram, ConZip. You can also find it on online pharmacies like 1mg, Pharmeasy and Apollo Pharmacy.
Tramadol is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.
Common side effects of Tramadol can include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Dry mouth, Insomnia. Less common but serious side effects can include: Severe, Serious, Life-threatening, Fatal, Death. Stop the medicine and contact your doctor immediately if any of these appear.
Although the mode of action of tramadol is not completely understood, the analgesic effect of tramadol is believed to be due to both binding to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin.
Tramadol can interact with: Tramadol, Hydrochloride, Clinical, Intervention, Evaluate, Quinidine. Tell your doctor about every medicine, supplement and herbal product you take — including ayurvedic and homeopathy preparations — before starting Tramadol.
Indian guidelines often recommend lower starting doses of Tramadol for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.
Pregnancy safety of Tramadol depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Tramadol during pregnancy or while planning conception.
Prices in India typically range from ₹10 – ₹120 per strip of 10 tablets depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.
If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Tramadol's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.
You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.
Medical Disclaimer
The content provided on Zospital is for general informational and educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call your doctor or emergency services immediately.