Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Secukinumab requires a valid prescription.
Secukinumab
Generic Name: SECUKINUMAB
11 DESCRIPTION Secukinumab, a recombinant human monoclonal IgG1/κ antibody, is an interleukin-17A antagonist.
Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)
Common Brand Names in India:
What is Secukinumab Used For?
- Adult patients with active ankylosing spondylitis (AS)
How Does It Work?
Secukinumab inhibits the release of proinflammatory cytokines and chemokines. 12.2 Pharmacodynamics Elevated levels of IL-17A are found in psoriatic plaques and in HS lesions.
Dosage & Administration
- Administer as an intravenous infusion after dilution over a period of 30 minutes. ( 2.11 ) Plaque Psoriasis: Subcutaneous Dosage in Adults: Recommended dosage is 300 mg by subcutaneous injection at Weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter.
- For some patients, a dose of 150 mg may be acceptable. ( 2.3 ) Subcutaneous Dosage in Pediatric Patients 6 Years and Older: Recommended weight-based dosage is administered by subcutaneous injection at Weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter.
- For patients < 50 kg, the dose is 75 mg.
Side Effects
Common Side Effects
Serious Side Effects (seek immediate medical attention)
Warnings & Precautions
- 5 WARNINGS AND PRECAUTIONS Infections : Serious infections have occurred.
- Exercise caution when considering the use of COSENTYX in patients with a chronic infection or a history of recurrent infection.
- Exercise caution when prescribing COSENTYX to patients with IBD. ( 5.4 ) Eczematous Eruptions : Cases of severe eczematous eruptions have occurred in patients receiving COSENTYX. ( 5.5 ) Immunizations : Avoid use of live vaccines in patients treated with COSENTYX. ( 5.7 ) 5.1 Infections COSENTYX may increase the risk of infections.
- A similar increase in risk of infection in subjects treated with COSENTYX was seen in placebo-controlled trials in subjects with PsA, AS and nr-axSpA.
- Exercise caution when considering the use of COSENTYX in patients with a chronic infection or a history of recurrent infection.
Who Should NOT Take This?
- 4 CONTRAINDICATIONS COSENTYX is contraindicated in patients with a previous serious hypersensitivity reaction to secukinumab or to any of the excipients in COSENTYX.
- Serious hypersensitivity to secukinumab or any excipients in COSENTYX. ( 4 )
Drug Interactions
Secukinumab may interact with the following medicines. Always inform your doctor about all medications you are taking.
Storage Instructions
Store at room temperature, away from moisture and heat.
Need a Prescription or Medical Advice?
Consult a qualified doctor before taking Secukinumab. Our verified doctors are available for in-clinic and online consultations.
Other Skin & Dermatology Medicines
Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.
FAQS
Secukinumab – Frequently Asked Questions
Common questions about Secukinumab, its uses, dosage and safety.
Secukinumab is used for: Adult patients with active ankylosing spondylitis (AS).
Secukinumab is available in India under the brand names: Cosentyx.
Secukinumab is a prescription-only medicine. You need a valid prescription from a registered doctor to purchase it.
Common side effects of Secukinumab include: Nausea, Diarrhea, Headache, Abdominal pain. Serious but less common side effects include: Severe, Serious, Anaphylaxis. Consult your doctor if you experience any severe symptoms.
Secukinumab inhibits the release of proinflammatory cytokines and chemokines. 12.2 Pharmacodynamics Elevated levels of IL-17A are found in psoriatic plaques and in HS lesions.
Secukinumab may interact with: Certain, Clinical. Always inform your doctor about all medicines, supplements, and herbal products you are taking.
Elderly patients may be more sensitive to Secukinumab. Dose adjustments are often needed due to reduced kidney and liver function. Always consult a doctor before use in patients over 65 years of age.
The safety of Secukinumab during pregnancy has not been fully established. Consult your obstetrician or gynaecologist before taking Secukinumab if you are pregnant or planning to become pregnant.
The price of Secukinumab varies by brand and formulation. Common brands include Cosentyx. Check with your local pharmacy or an online pharmacy for current pricing. Generic versions are generally more affordable than branded ones.
If you miss a dose of Secukinumab, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. Consult your doctor if you frequently forget doses.
Medical Disclaimer
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