CGHS Rates for Immunology & Autoimmune Laboratory Tests

Immunology and autoimmune laboratory tests are crucial diagnostic tools used to identify and monitor disorders of the immune system. These conditions occur when the body's immune system mistakenly attacks its own tissues, causing inflammation and damage.

Physicians, particularly rheumatologists, immunologists, and nephrologists, rely on these tests to diagnose conditions such as systemic lupus erythematosus (SLE), rheumatoid arthritis, celiac disease, myositis, and various vasculitides. Tests like the Antinuclear Antibody (ANA) screen are often a starting point, followed by more specific antibody tests to confirm a diagnosis.

This page provides the approved Central Government Health Scheme (CGHS) rates for a comprehensive list of these specialized laboratory tests. Beneficiaries can use this guide to understand the costs covered under the scheme at CGHS-empanelled hospitals and diagnostic centres. The rates vary based on the specific test and the accreditation status (NABH or non-NABH) of the facility. Please refer to the rate table for detailed pricing information.

CGHS Immunology & Autoimmune Test Rates (effective 13 October 2025)

• Immunoglobulin G (IgG), Non-NABH — Rs 340
• Immunoglobulin G (IgG), NABH — Rs 400
• Immunoglobulin M(IgM), Non-NABH — Rs 340
• Immunoglobulin M(IgM), NABH — Rs 400
• Immunoglobulin A(IgA), Non-NABH — Rs 340
• Immunoglobulin A(IgA), NABH — Rs 400
• Antinuclear Antibody (ANA), Non-NABH — Rs 557
• Antinuclear Antibody (ANA), NABH — Rs 655
• Anti-double stranded DNA (anti-dsDNA), Non-NABH — Rs 680
• Anti-double stranded DNA (anti-dsDNA), NABH — Rs 800
• CD 3,4 and 8 Counts, Non-NABH — Rs 1,054
• CD 3,4 and 8 Counts, NABH — Rs 1,240
• CD 3,4 and 8 Percentage, Non-NABH — Rs 1,284
• CD 3,4 and 8 Percentage, NABH — Rs 1,510
• Direct Immunofluorescence (Skin and Kidney Disease etc), Non-NABH — Rs 1,020
• Direct Immunofluorescence (Skin and Kidney Disease etc), NABH — Rs 1,200
• Indirect (anti ds DNA Anti Smith ANCA), Non-NABH — Rs 1,020
• Indirect (anti ds DNA Anti Smith ANCA), NABH — Rs 1,200
• Serum Protein electrophoresis with immunofixation electrophoresis (IFE), Non-NABH — Rs 595
• Serum Protein electrophoresis with immunofixation electrophoresis (IFE), NABH — Rs 700
• Anti-Cyclic Citrullinated Peptide (Anti CCP), Non-NABH — Rs 765
• Anti-Cyclic Citrullinated Peptide (Anti CCP), NABH — Rs 900
• Anti-tissue Transglutaminase antibody (Anti TTG Antibody) / Tissue Transglutaminase IgA (tTg-IgA), Non-NABH — Rs 680
• Anti-tissue Transglutaminase antibody (Anti TTG Antibody) / Tissue Transglutaminase IgA (tTg-IgA), NABH — Rs 800
• Islet cell antibody, Non-NABH — Rs 1,020
• Islet cell antibody, NABH — Rs 1,200
• Glutamic Acid Decarboxylase Autoantibodies test (GAD antibodies), Non-NABH — Rs 1,700
• Glutamic Acid Decarboxylase Autoantibodies test (GAD antibodies), NABH — Rs 2,000
• Insulin associated antibody, Non-NABH — Rs 833
• Insulin associated antibody, NABH — Rs 980
• Kappa Lambda Light Chains, Free, Serum/ Serum free light chains (SFLC), Non-NABH — Rs 3,421
• Kappa Lambda Light Chains, Free, Serum/ Serum free light chains (SFLC), NABH — Rs 4,025
• Serum IgE Level, Non-NABH — Rs 323
• Serum IgE Level, NABH — Rs 380
• Anti –Smooth Muscle Antibody Test (ASMA), Non-NABH — Rs 1,241
• Anti –Smooth Muscle Antibody Test (ASMA), NABH — Rs 1,460
• C ANCA-IFA, Non-NABH — Rs 1,275
• C ANCA-IFA, NABH — Rs 1,500
• P ANCA-IFA, Non-NABH — Rs 1,275
• P ANCA-IFA, NABH — Rs 1,500
• Extractable Nuclear Antigens (ENA) - Quantitative, Non-NABH — Rs 3,910
• Extractable Nuclear Antigens (ENA) - Quantitative, NABH — Rs 4,600
• C3-COMPLEMENT, Non-NABH — Rs 553
• C3-COMPLEMENT, NABH — Rs 650
• C4-COMPLEMENT, Non-NABH — Rs 553
• C4-COMPLEMENT, NABH — Rs 650
• Interleukin 6 (IL 6), Non-NABH — Rs 1,360
• Interleukin 6 (IL 6), NABH — Rs 1,600
• Cryoglobulins, Non-NABH — Rs 850
• Cryoglobulins, NABH — Rs 1,000
• PLA2 receptor antibody quantitative, Non-NABH — Rs 3,570
• PLA2 receptor antibody quantitative, NABH — Rs 4,200
• AMA (Anti Mitochondrial Antibody), Non-NABH — Rs 850
• AMA (Anti Mitochondrial Antibody), NABH — Rs 1,000
• ANA BLOT, Non-NABH — Rs 2,550
• ANA BLOT, NABH — Rs 3,000
• ANA Profile, Non-NABH — Rs 2,550
• ANA Profile, NABH — Rs 3,000
• Anti GBM (Glomerular Basement Membrane) Antibody, Non-NABH — Rs 1,275
• Anti GBM (Glomerular Basement Membrane) Antibody, NABH — Rs 1,500
• Anti LKM (Liver Kidney Microsome) Ab, Non-NABH — Rs 1,275
• Anti LKM (Liver Kidney Microsome) Ab, NABH — Rs 1,500
• Anti Parietal Cell Antibodies, Non-NABH — Rs 1,700
• Anti Parietal Cell Antibodies, NABH — Rs 2,000
• Anti Intrinsic Factor Antibodies, Non-NABH — Rs 1,700
• Anti Intrinsic Factor Antibodies, NABH — Rs 2,000
• ASO Titre /ASLO Titre, Non-NABH — Rs 459
• ASO Titre /ASLO Titre, NABH — Rs 540
• Aspergillus Fumigatus Specific IgE, Non-NABH — Rs 1,318
• Aspergillus Fumigatus Specific IgE, NABH — Rs 1,550
• Autoimmune Encephalitis Panel, Non-NABH — Rs 14,450
• Autoimmune Encephalitis Panel, NABH — Rs 17,000
• Autoimmune Hepatitis Profile, Non-NABH — Rs 2,516
• Autoimmune Hepatitis Profile, NABH — Rs 2,960
• C1 Esterase inhibitor (Quantitative ), Non-NABH — Rs 2,040
• C1 Esterase inhibitor (Quantitative ), NABH — Rs 2,400
• IgG4, Non-NABH — Rs 1,700
• IgG4, NABH — Rs 2,000
• Serum AMA M2 (IFA Method), Non-NABH — Rs 1,700
• Serum AMA M2 (IFA Method), NABH — Rs 2,000
• Myositis Profile (Up to 16 Antigens), Non-NABH — Rs 6,800
• Myositis Profile (Up to 16 Antigens), NABH — Rs 8,000
• Paraneoplastic Panel, Non-NABH — Rs 8,500
• Paraneoplastic Panel, NABH — Rs 10,000
• Anti-Nuclear Antibodies - IFA, Non-NABH — Rs 1,360
• Anti-Nuclear Antibodies - IFA, NABH — Rs 1,600
• Autoimmune Liver Diseases Profile, Non-NABH — Rs 4,250
• Autoimmune Liver Diseases Profile, NABH — Rs 5,000
• Comprehensive Myeloma Protein Panel, Non-NABH — Rs 5,950
• Comprehensive Myeloma Protein Panel, NABH — Rs 7,000
• Desmoglein (DSG) 1 And 3 Antibody, Non-NABH — Rs 4,590
• Desmoglein (DSG) 1 And 3 Antibody, NABH — Rs 5,400
• SCL 70 Antibody, Non-NABH — Rs 1,428
• SCL 70 Antibody, NABH — Rs 1,680
• SSA- Antibody Ro Serum Test, Non-NABH — Rs 1,233
• SSA- Antibody Ro Serum Test, NABH — Rs 1,450
• SSB- Antibody La Serum Test, Non-NABH — Rs 1,233
• SSB- Antibody La Serum Test, NABH — Rs 1,450

Rates shown are as per the CGHS approved package rates (Office Memorandum F.No.5-16/CGHS(HQ)/HEC/2024(PartI) dated 03.10.2025, effective 2025-10-13) (2025 (effective 13.10.2025)) and are subject to periodic revision. Always verify the latest approved rates on the official source.

Who this covers

This rate guide is intended for CGHS beneficiaries who have been advised by a specialist to undergo specific laboratory tests to investigate or monitor an immune-related condition. These tests are not routine and are typically prescribed when there is a clinical suspicion of an autoimmune disorder.

The procedures listed are relevant for individuals presenting with symptoms such as persistent joint pain, skin rashes, unexplained fever, fatigue, muscle weakness, or organ-specific issues that suggest an autoimmune cause. This includes investigations for conditions like lupus, rheumatoid arthritis, celiac disease, autoimmune liver disease, myositis, and certain neurological syndromes.

The list covers a wide array of tests, from foundational screenings like ANA and immunoglobulin levels (IgG, IgM, IgA) to highly specific panels like the Myositis Profile, Paraneoplastic Panel, and Autoimmune Encephalitis Panel. A valid prescription from a government or CGHS-recognized specialist is required to avail these tests under the scheme.

What CGHS covers vs. what you pay separately

The CGHS rates published in the table on this page represent the full reimbursement amount for the laboratory procedure itself. This includes the cost of running the test using standard methods and the generation of the report by the empanelled diagnostic lab or hospital.

Beneficiaries should be aware that certain items may not be included in the package rate and could be billed separately. While less common for laboratory tests compared to surgical procedures, this could potentially include special test kits or reagents if they are not considered standard. The cost of home sample collection, if offered and chosen by the beneficiary, is typically an additional expense.

It is advisable to clarify the total cost and any potential extra charges with the hospital's billing department before the sample is collected. Ensure you get a clear breakdown of what is covered by the CGHS rate and what is not.

How to use this at a CGHS-empanelled hospital

To avail these tests at an empanelled facility, you must present your CGHS card along with a valid and detailed prescription from a government specialist or a CGHS-empanelled doctor. The prescription should clearly state the specific test(s) required (e.g., 'Anti-dsDNA', 'C3/C4 Complement Levels').

When you are at the hospital or diagnostic centre, present your documents at the CGHS counter. The staff will match the prescribed test with the corresponding procedure name and code in the CGHS list. It is prudent to double-check the test name on the billing request form to ensure it matches your doctor's prescription exactly.

The applicable rate is determined by the accreditation of the hospital or lab, not by the beneficiary's choice. Facilities with NABH (National Accreditation Board for Hospitals & Healthcare Providers) accreditation are eligible for a higher rate than non-NABH accredited facilities. This distinction is handled automatically by the billing system of the empanelled centre.

Frequently Asked Questions

What is an Antinuclear Antibody (ANA) test and why is it prescribed?

The ANA test detects autoantibodies that target components within the nucleus of a cell. A positive result can indicate an autoimmune reaction. It is often used as an initial screening test for individuals with symptoms suggestive of a systemic autoimmune disease like lupus, scleroderma, or Sjögren's syndrome. A positive ANA test usually requires further, more specific antibody testing to pinpoint a diagnosis.

Do I need to fast for these immunology blood tests?

For most immunology and autoantibody tests, including ANA, anti-dsDNA, and immunoglobulin levels, fasting is generally not required. However, if your doctor has ordered other blood tests at the same time (like a lipid profile or blood sugar test), fasting may be necessary for those. Always follow the specific instructions given by your doctor or the laboratory.

My doctor ordered an 'ENA Panel.' Is that covered?

Yes, the CGHS list includes 'Extractable Nuclear Antigens (ENA) - Quantitative'. An ENA panel is a group of blood tests used to detect specific autoantibodies in individuals who have a positive ANA test. These antibodies (like Anti-SSA/Ro, Anti-SSB/La, Anti-Smith) help in diagnosing specific autoimmune diseases. Confirm the exact test name with the lab to ensure correct billing under the CGHS code.

Are Myositis Profile and Paraneoplastic Panel tests covered by CGHS?

Yes, the updated CGHS list explicitly includes rates for 'Myositis Profile (Up to 16 Antigens)' and 'Paraneoplastic Panel'. These are highly specialized tests used to diagnose autoimmune muscle diseases (myositis) and neurological disorders triggered by an underlying cancer (paraneoplastic syndromes), respectively. A specialist's prescription is essential for these tests.

What is the difference between a direct and indirect immunofluorescence test?

Both are methods to detect antibodies, and both are covered under CGHS. Direct Immunofluorescence (DIF) is typically used on tissue samples (like a skin or kidney biopsy) to find antibodies that are already attached to the tissue. Indirect Immunofluorescence (IIF) is used on a serum (blood) sample to find circulating antibodies. For example, IIF is a common method for ANA and ANCA testing.

How do I get a referral for these specialized tests?

To get these tests done under CGHS, you generally need a referral from a specialist at a government hospital or a CGHS Wellness Centre. If you consult a specialist at a CGHS-empanelled private hospital, they can also prescribe these tests, which can then be done at an empanelled facility. A general practitioner's prescription may not be sufficient for these high-end investigations.

The hospital is charging for items I thought were covered. What should I do?

If you believe you are being charged for items that should be included in the CGHS package rate, first raise the issue with the hospital's billing department and ask for a detailed, itemized bill. Refer them to the specific CGHS order. If the issue is not resolved, you can file a grievance with the CGHS authorities through the official channels, providing copies of your prescription, bills, and CGHS card.

Related

• How to apply for a CGHS card
• CGHS rate list for common procedures
• CGHS vs Ayushman Bharat: what's the difference

Medical Disclaimer

The information provided in this article is for general informational and educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in this article.