Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Voriconazole requires a valid prescription.

AntifungalsPrescription RequiredINTRAVENOUS

Voriconazole

Generic Name: VORICONAZOLE

11 DESCRIPTION VFEND (voriconazole), an azole antifungal agent is available as a lyophilized powder for solution for intravenous infusion.

Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)

Common Brand Names in India:

Vfend

What is Voriconazole Used For?

  • Invasive aspergillosis (IA)
  • Esophageal candidiasis (EC) [see Clinical Studies (14

How Does It Work?

A pharmacokinetic-pharmacodynamic analysis of patient data from 6 of these 10 clinical trials (N=280) could not detect a positive association between mean, maximum or minimum plasma voriconazole concentration and efficacy.

Dosage & Administration

  • Administer diluted VFEND I.V. by intravenous infusion over 1 to 3 hours only.
  • Do not administer as an IV bolus injection. 2.2 Use of VFEND I.V. with Other Parenteral Drug Products Blood products and concentrated electrolytes VFEND I.V. must not be infused concomitantly with any blood product or short-term infusion of concentrated electrolytes, even if the two infusions are running in separate intravenous lines (or cannulas).
Always follow your doctor's prescription. Do not self-medicate or change doses without medical advice.

Side Effects

Common Side Effects

NauseaVomitingDiarrheaConstipationHeadacheDizzinessDry mouthInsomnia

Serious Side Effects (seek immediate medical attention)

SevereSeriousDeathAgranulocytosisAplastic

Warnings & Precautions

  • 5 WARNINGS AND PRECAUTIONS Hepatic Toxicity : Serious hepatic reactions reported.
  • Hepatic reactions, including hepatitis and jaundice, have occurred among patients with no other identifiable risk factors.

Who Should NOT Take This?

  • There is no information regarding cross-sensitivity between VFEND and other azole antifungal agents.

Drug Interactions

Voriconazole may interact with the following medicines. Always inform your doctor about all medications you are taking.

ClinicalInteractionPreventionRifampinRifabutinInductionCarbamazepineReduction

Storage Instructions

16.2 Storage VFEND I.V. for Injection unreconstituted vials should be stored at 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].

Speak to a dermatologist on Zospital

Consult a dermatologist on Zospital before starting Voriconazole. Verified Indian specialists available for in-clinic and online consultations.

Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.

FAQS

Voriconazole – Frequently Asked Questions

Common questions about Voriconazole, its uses, dosage and safety.

Voriconazole is commonly prescribed in India for: Invasive aspergillosis (IA), Esophageal candidiasis (EC) [see Clinical Studies (14. Always confirm the indication with a registered medical practitioner before starting any course.

Voriconazole is sold in India under brand names such as Vfend. You can also find it on online pharmacies like 1mg, Pharmeasy and Apollo Pharmacy.

Voriconazole is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.

Common side effects of Voriconazole can include: Nausea, Vomiting, Diarrhea, Constipation, Headache, Dizziness, Dry mouth, Insomnia. Less common but serious side effects can include: Severe, Serious, Death, Agranulocytosis, Aplastic. Stop the medicine and contact your doctor immediately if any of these appear.

A pharmacokinetic-pharmacodynamic analysis of patient data from 6 of these 10 clinical trials (N=280) could not detect a positive association between mean, maximum or minimum plasma voriconazole concentration and efficacy.

Voriconazole can interact with: Clinical, Interaction, Prevention, Rifampin, Rifabutin, Induction. Tell your doctor about every medicine, supplement and herbal product you take — including ayurvedic and homeopathy preparations — before starting Voriconazole.

Indian guidelines often recommend lower starting doses of Voriconazole for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.

Pregnancy safety of Voriconazole depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Voriconazole during pregnancy or while planning conception.

Prices in India typically range from ₹30 – ₹500 per strip / vial depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.

If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Voriconazole's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.

You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.

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