Not medical advice. This information is for educational purposes only. Always consult a qualified doctor or pharmacist before taking any medicine. Ceftriaxone requires a valid prescription.

AntibioticsPrescription RequiredINTRAMUSCULAR

Ceftriaxone

Generic Name: CEFTRIAXONE SODIUM

DESCRIPTION Ceftriaxone for injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration.

Data last updated: 30 March 2026 · Source: openFDA.gov, DailyMed (NLM/NIH)

Common Brand Names in India:

MonocefRocephinXtumCeftraxCeftriaxone Sodium

What is Ceftriaxone Used For?

  • Therapy may be instituted prior to obtaining results of susceptibility testing.

How Does It Work?

Ceftriaxone is reversibly bound to human plasma proteins, and the binding decreased from a value of 95% bound at plasma concentrations of < 25 mcg/mL to a value of 85% bound at 300 mcg/mL.

Dosage & Administration

  • DOSAGE AND ADMINISTRATION Ceftriaxone may be administered intravenously or intramuscularly.
Always follow your doctor's prescription. Do not self-medicate or change doses without medical advice.

Side Effects

Common Side Effects

NauseaVomitingDiarrheaHeadacheDizzinessRashAbdominal painFlushing

Serious Side Effects (seek immediate medical attention)

SevereFatalAnaphylaxisAnaphylacticAgranulocytosis

Warnings & Precautions

  • Antibacterial drugs should be administered with caution to any patient who has demonstrated some form of allergy, particularly to drugs.
  • Interaction with Calcium-Containing Products Do not use diluents containing calcium, such as Ringer’s solution or Hartmann’s solution, to reconstitute ceftriaxone vials or to further dilute a reconstituted vial for IV administration because a precipitate can form.

Who Should NOT Take This?

  • CONTRAINDICATIONS Hypersensitivity Ceftriaxone for injection is contraindicated in patients with known hypersensitivity to ceftriaxone, any of its excipients or to any other cephalosporin.
  • Neonates Premature neonates : Ceftriaxone for injection is contraindicated in premature neonates up to a post-menstrual age of 41 weeks (gestational age + chronological age).
  • Hyperbilirubinemic neonates : Hyperbilirubinemic neonates should not be treated with ceftriaxone for injection.
  • Ceftriaxone can displace bilirubin from its binding to serum albumin, leading to a risk of bilirubin encephalopathy in these patients.

Storage Instructions

Storage Prior to Reconstitution Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].

Speak to a general physician on Zospital

Consult a general physician on Zospital before starting Ceftriaxone. Verified Indian specialists available for in-clinic and online consultations.

Sources: openFDA.gov · dailymed.nlm.nih.gov · nlm.nih.gov (RxNorm). Information is for educational purposes only. Consult a doctor before use.

FAQS

Ceftriaxone – Frequently Asked Questions

Common questions about Ceftriaxone, its uses, dosage and safety.

Ceftriaxone is commonly prescribed in India for: Therapy may be instituted prior to obtaining results of susceptibility testing.. Always confirm the indication with a registered medical practitioner before starting any course.

Ceftriaxone is sold in India under brand names such as Monocef, Rocephin, Xtum, Ceftrax, Ceftriaxone Sodium. You can also find it on online pharmacies like 1mg, Pharmeasy and Apollo Pharmacy.

Ceftriaxone is a prescription-only (Schedule H) medicine in India. You will need a valid prescription from a registered MBBS / MD doctor to purchase it from a licensed pharmacy.

Common side effects of Ceftriaxone can include: Nausea, Vomiting, Diarrhea, Headache, Dizziness, Rash, Abdominal pain, Flushing. Less common but serious side effects can include: Severe, Fatal, Anaphylaxis, Anaphylactic, Agranulocytosis. Stop the medicine and contact your doctor immediately if any of these appear.

Ceftriaxone is reversibly bound to human plasma proteins, and the binding decreased from a value of 95% bound at plasma concentrations of < 25 mcg/mL to a value of 85% bound at 300 mcg/mL.

Indian guidelines often recommend lower starting doses of Ceftriaxone for patients above 60-65, since kidney and liver function decline with age. A doctor should review the dose, especially if the patient already takes BP, sugar or heart medicines.

Pregnancy safety of Ceftriaxone depends on the trimester and individual case. Indian gynaecologists usually avoid Category C/D drugs unless benefit clearly outweighs risk. Speak to your obstetrician before taking Ceftriaxone during pregnancy or while planning conception.

Prices in India typically range from ₹40 – ₹400 per strip of 10 tablets depending on brand. Generic versions tend to cost 30-60% less than branded ones, and Jan Aushadhi outlets often stock the lowest-priced equivalents. Check 1mg or Pharmeasy for live MRP.

If you remember within a few hours of the missed dose, take it. If it is nearly time for the next dose, skip the missed one — never double up. Frequent missed doses reduce Ceftriaxone's effectiveness, so consider setting a reminder or speaking to your doctor about a simpler schedule.

You can book an in-person or online consultation with a verified Indian specialist on Zospital — visit the doctor directory at https://zospital.com/doctor to find one near you.

Medical Disclaimer

The content provided on Zospital is for general informational and educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call your doctor or emergency services immediately.

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